Sustanon was available after 1937 as one of the effective testosterone blends; you can find the steroid marketed commercially as Sustanon 250.[1] It’s made for the treatment of infrequent Testosterone Replacement Therapy (TRT) which is a class of androgens hormone replacement therapy.[2]

Sustanon was formulated by Organon International, which are primarily specialized in the therapeutic areas for the psychiatry, contraception, reproduction, anesthesia and the hormone replacement therapy known as HRT. After a series of acquisition and merger, the pharmaceutical company presently is part of Merck & Co.

The initial purpose of Sustanon is for treating testosterone deficiency and androgen deficiency. Sustanon regulates testosterone level when the natural testosterone hormone production in the body is low.[3]

However, the drug is abused by athletes for performance enhancing purposes in the sports. Sustanon including testosterone and its esters were classified as an anabolic androgenic steroids or AAS. The steroid frequently exploits by the bodybuilders to improve endurance, strength and muscle development.

Following numbers of scandals, publicity of the steroid abuse in the 1980s. The uses of anabolic androgenic steroids were prohibited in the sports. In 1990, the United States Congress designated AAS and testosterone as a controlled substance with the Anabolic Steroid Control Act.[4]


Sustanon is a mixture of numerous testosterone esters that was introduced to handle the low level of endogenous testosterone as a hormone replacement therapy.  The steroid is an oil based injectable form of esterized testosterone compound in clear pale yellow color.


There are four types of testosterone that are found in Sustanon 250. Each type of this steroid’s testosterone has different absorption rate, which takes care of the level of anabolic hormones in the user’s blood within a month.

Originally, Sustanon was created to allow the user experience a prolong testosterone effect. With an injection, a TRT patient can get a high testosterone every 3-4 weeks.[2]

Sustanon has the capacity to enhance protein synthesis significantly. The synthesis of protein represents the level of cells building proteins. This process is vital in the muscle building as proteins are essential for the expansion of muscle tissues. Sustanon promotes nitrogen retention in muscles for immediate recovery in the workout.

Sustanon enhances the production of insulin releases that is responsible for boosting the red blood cell count and improves the body recovery process.[5] As the red blood cells are known to transport oxygen, which will increase the muscle’s ability to recover and endure from the stress.

Uses of Sustanon

Sustanon is known to deepen the voices of men. It is used to treat people who no natural or low testosterone in a condition has called hypogonadism.[3] The drug is used in taking of osteoporosis in men that is caused by the deficiency of androgen. It helps to regulate the testosterone levels in a normal range.[2]

Sustanon is used to help people gain mass within a short time without accumulating fat. The steroid is going to offer a high calorie quality that will increase strength and build the user’s lean muscle. The drug improves and increases the body metabolism.

Sustanon, testosterone, including its esters have been used in the improvement of endurance, strength and muscle development. The direct protein synthesis process promotes the muscle growth more rapidly than average rate. Hence the muscle fibers are enlarged and recovery is enhanced within a short period of time.

Lower doses of testosterone are used for a short term treatment in women with hypoactive sexual desire disorder. It is also used to improve orgasm, sexual activity, sexual satisfaction and arousal in postmenopausal women.[6]

Transgender men use the drug as a hormone therapy to achieve male’s testosterone level.[1]

Sustanon Effects

Sustanon is known to be effective when it comes to the bulking cycle. As testosterone levels play an important role in the muscle growth. However the calories must be present in the body in order to create a perfect condition that will allow the muscle to grow. The high amount of testosterone will ensure that there is a significant lean muscle growth. This will also greatly increases the metabolic rate in the body.

Sustanon Effects

Sustanon work effectively in the cutting cycle as well. It preserves the lean tissues whenever it can while restricting the calories. This is essential for building lean muscles efficiently. As to burn an excessive fat in the body, we have to burn more calories than what we take. When this happens, frequently the lean tissues disappear in the fat burning progress. However, the powerful anabolic nature of Sustanon will preserve the lean muscle. It will cause the body fat to be burnt instead of the muscles.

The body fat is burnt fast and more effectively because of the metabolic enhancement effect. As a result of estrogen sensitivity found in Sustanon, the recovery rate and muscular endurance are greatly enhanced.

Sustanon increase the red blood cell production in the body.[5] This is important in the oxygen transportation to the muscles for recovery. It supports the promotion of the cellular regeneration. This is vital because it prevents the wasting of muscle tissues. Users feel more powerful and stronger, and they can perform better and longer.

Sustanon Side Effects

The Food and Drug Administration (FDA) demanded that the labels of testosterone should have warning information. Which the drug may possibly increase the risk of stroke and heart attacks.[7] The adverse effects of testosterone related supplementation may include the possibility of increase cardiovascular problems and death.

Sustanon Side Effects

Sustanon like every other type of testosterone, it is transformed into estrogens. Anabolic steroid can cause side effects such as edema or swelling, enlarged breast in men (gynecomastia), suppression of the production of testosterone and deposition of fat.[3]

High levels of testosterone use in women can cause deepened of their voice, excessive facial and body hair growth known as hirsutism and other virilization symptoms. Androgens like testosterone can cause fetal harm such as born with large clitoris or small penis (ambiguous genitalia).[8]

Testosterone in the body can be transformed into dihydrotestosterone that can cause side effects like seborrhea, acne and oily skin, including loss of scalp hair, baldness, prostate, and others.[8]

Athletes often report issues like flu like situations and fever while making use of Sustanon. Like other anabolic steroids, Sustanon may increase the level of the body’s cholesterol which is harmful.

Breast tenderness and gynecomastia can occur when it is taken in high dose. In high doses, it can change the mood, increase sex drive, aggression, nocturnal emissions and spontaneous erections.[8]

There are other effects like increases the red blood cell ratio to total volume (hematocrit) and worsening of sleep apnea. More serious of the side effects includes liver toxicity and heart disease.[8]

Sustanon Alternative

Sustanon is a great steroid that is hampered by side effects. It can be potentially harmful to the body with some effects yet to be discovered.  It is not intended for performance enhancement for bodybuilders because it is mostly used for therapeutic functions.

Testosterone is an alternative to Sustanon. It is used in increasing the strength, sex drive and testosterone levels for men.  Legal steroid is effective and is safer to use compared to Sustanon anabolic steroid that required injection.

Sustanon Alternative


  1. (1998) Testosterone: Action – Deficiency – Substitution

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