Proviron is an anabolic androgenic steroid of Mesterolone. The drug is a product of Schering. It first manufactured and released to the market in 1934. The drug was the first steroid that was sold on the market and followed by methyltestosterone in 1936.[1] Both medications are for the treatment of low testosterone levels.

The primary function of Proviron is for muscle mass enhancement. It is taken as testosterone booster. It is used in treating patients who have cannot produce hormones.[2] But bodybuilders take advantage of the drug to enhance their physique and performances.

Mesterolone works by inhibiting the production of estrogen, improves the testosterone potency and increase the muscle hardness and density and lowers the male libido.

Elsewhere the drug is said to improve libido and energy including the overall well-being. Proviron are prescribed to men who are suffering from male menopause, a condition that happens when the level of testosterone is reduced due to age.

Proviron become one of anabolic androgenic steroids (AAS) recognized for its therapeutic agent. Although they are used in modern medicine, but the Mesterolone hormone is not recognized by the United States FDA.[1]

It has become a controlled substance in different countries and is considered illicit for non medical purposes.


Like another anabolic androgenic steroid (AAS), the drug is known as androgen receptor agonist. It is not a strong anabolic agent and relatively low in its anabolic and androgenic potency. It is not aromatase and cannot be converted into estrogen.

Proviron is a dihydrotestosterone (DHT) derived AAS that structurally alters the DHT hormone. The drug has an extra methyl group instead of the C17-alpha alkylated. This is why it allows the DHT to survive when it is orally digested.

The drug is not popular among athletes and bodybuilders because it has a low anabolic activity on the body. Proviron can inhibit the aromatase activity by binding to the enzyme. This ensures that it protects the user against estrogenic side effects.

The Proviron hormone carries a binding affinity to the receptors of androgen. It promotes the metabolic functionality through direct lipolysis.

One of the characteristics of Proviron is that doesn’t affect gonadotropins and has a potent androgenicity. The strong affinity to androgencity is what improves the sperm production.[3]


Mesterolone is unique when it is compared to other AAS in terms of its high affinity for human serum sex hormone-binding globulin (SHBG). SHBG inhibit and decreasing free testosterone to some extent. The ability to bind to this sex hormone makes more testosterone to be released without constraint.

Uses of Proviron

Mesterolone is used in treating people with anaemia and androgen deficiency, especially in diminished function of male sex hormone functional (hypogonadism).[4] The drug is used in the treatment of delayed puberty in adolescents.

Proviron is used primarily for treating low testosterone levels in men. It uses in the treatment of low level of natural androgen.[2] The steroid functions by supplementing the male hormone that naturally produces in the body.

Mesterolone is a weak androgen and may not be used for androgen replacement therapy. However, it is used in the androgen deficiency treatment when there is a sign of gynecomastia or breast tenderness.[5] This is because it does not affect estrogen.

Proviron used for fertility treatment on males with low sperm count. It is not only stimulates spermatogenesis but improves the well being of the sperm.[3]

The drug is used in the treatment of erectile malfunction and low libido. It was suggested medications for male’s impotent treatment. Though, its use for treating impotency is still unknown and controversial.

In bodybuilding, the steroid is used by powerlifters, bodybuilders and athletes for performance-enhancing purposes and muscle mass again. Proviron is recommended for use in male patients for now because it supplements the body’s natural male sex hormones.

Proviron Effects

Proviron improves the total free-state when it is used alongside other steroids during stacking. Bodybuilders make use of a large amount of Mesterolone during the bulking phase, but there is a reduced testosterone plan during the cutting phase.

Proviron Effects

It gives the required androgen support for people who are comfortable with low testosterone dosage during the cutting phase. The drug has proven to be effective in boosting its androgen. The best time you can use Proviron is during the cutting cycle. The ability of this steroid to give the user a hardening effect is what most people look out for.

The anti-estrogen effect of the steroid ensures that the user does not suffer from water retention. When the testosterone level is low, Proviron successfully boosts its androgenic effect to support the user. The androgencity of the steroid is used in promoting a more refined body structure.

The steroid does not have a progestin nature and have less effect on water retention or gynecomastia. The risk of getting high blood pressure is reduced because it cannot retain water.

Proviron Side Effects

As Mesterolone is an anabolic steroid of dihydrotestosterone (DHT). It carries all the primary side effects of the DHT in nature. The DHT effect is well known for causing of acne.

Proviron may have side effects but it is one of the less invasive anabolic steroids. Some men may not suffer any nasty side effect. The steroid is not recommended to be used in the women when it comes to performance and therapeutic capacity. The virilization effect is exceptionally high and should be avoided among the females.[1]

Proviron Side Effects

Proviron has androgenic effects that include acceleration of hair loss for those predisposed to male pattern baldness, acne and body hair growth. The potent androgenicity of this steroid can cause harsh virilization in women. The virilization effects include deepening of the vocal chords, body hair growth and clitoral enlargement.[1]

While the long term use of Proviron may cause sleep apnea, epilepsy, high blood pressure, cause kidney or liver disease, and heart or blood vessel disease.[6]

When taken in overdose, it may cause life threatening conditions such as difficult to pass urine and prostate enlargement.[6]

There are other side effects of the drug like depression, aggression, headache and increased sexual drive.[7]

Proviron Alternative

A legal alternative to Proviron or Mesterolone for increases of free testosterone. It is not toxic, neither does it have side effects like Proviron. It is among the natural testosterone boosters substitute with the similar effects.

The expectation of this alternative is extremely high because it promises the user improvement in areas such as libido, energy, strength and muscle mass. Proviron alternative promotes natural testosterone without side effects.

Proviron Alternative


  1. (2011) Anabolics By William Llewellyn